Journal of Yeungnam Medical Science

Mee Young Park

9 Articles

Diagnosis and Treatment of Parkinson's Disease Dementia : An Update: Mee Young Park; Yeungnam Univ J Med. 2007;24(2 Suppl):S159-169. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S159

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Abstract PDF: Dementia in the Parkinson’s disease has been increasingly recognized especially in old age. And akinetic-rigid symptoms or cognitive impairment at onset of Parkinson’s disease (PD) are also high risk factors for dementia. However, there have been no gold standard guideline in order to identify the Parkinson’s disease dementia (PDD). Recently, the Movement Disorder Society developed a new diagnostic criteria for PDD in December 2007. I introduce a new PDD diagnostic criteria proposal with a review of treatment strategy of PDD. After the sensitivity and specificity of these criteria ascertained, a revision may be need. But they promising clinical and prospective research baselines in the future.

Relationship between Clinical Grading of Carpal Tunnel Syndrome and Electrophysiological Parameter: Hyun Chul Do, Jun Lee, Se Jin Lee, Mee Young Park, Jung Sang Hah; Yeungnam Univ J Med. 2007;24(2 Suppl):S407-415. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S407

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Abstract PDF: Background
：To investigate the relationship between clinical grading and electrophysiological parameter in carpal tunnel syndrome. Materials and Methods：This studies examined 75 outpatients (100 hands) who were diagnosed as carpal tunnel syndrome at neurologic clinic from March to July in 2006. They were divided into three groups by clinical grading and then each groups were compared with sensory nerve conduction velocity (SNCV) and sensory compound nerve action potential (CNAP) amplitude of I-W, F-W, and P-W segments, motor terminal latency (TL), motor compound muscle action potential (CMAP) amplitude of distal segment, and disto-proximal ratio on the third finger.
Results
：The first group(mild) was 46 (51 hands) patients, second group(moderate) was 29 (35 hands) patients, and the third group (severe) was 14(14 hands) patients. The mean ages were 55.9, 57.4 and 57.0 years in each group, and there were no statistical differences in age and sex between 3 groups. SNCV of I-W, F-W and P-W segments and motor TL were different significantly between 3 groups, but disto-proximal ratio on the third finger was not different significantly(P<0.05). Motor TL was correlated with clinical grading. And also sensory CNAP amplitude of I-W, F-W, and P-W segments, and motor CMAP amplitude of distal segment were different significantly between 3 groups. Especially, sensory CNAP amplitude of P-W segment and motor TL were correlated with higher clinical grading groups(2, 3 groups)(p<0.05).
Conclusion
：SNCV of F-W and P-W segments, motor TL, motor CMAP amplitude of distal segment and sensory CNAP amplitude of each segments were correlated with the clinical grading of carpal tunnel syndrome.

A Family of Dentatorubropallidoluysian Atrophy.: Ji Yoon Chung, Mee Young Park, Jun Lee, Jun Pil Yoon, Hyun Jung Park; Yeungnam Univ J Med. 2006;23(1):118-123. Published online June 30, 2006; DOI: https://doi.org/10.12701/yujm.2006.23.1.118

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Abstract PDF: Dentatorubropallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder usually inherited in an autosomal dominant pattern. DRPLA has been shown to be associated with expansion of an unstable cytosine-adenine-guanine (CAG) trinucleotide repeat in a gene on chromosome 12p. We evaluated a family with DRPLA that affected three members; A 35-year-old female presented with seven year history of gait ataxia, dysarthria and mild cognitive impairment. The MRI of the brain revealed diffuse cerebellar atrophy with an incidental lipoma in the midbrain. Her 30-year-old brother presented with progressive cerebellar ataxia that developed at the age of 20. Her grandmother and mother were reported to have developed ataxia during the late period of their life, and died at the age of 60 and 55, respectively. The demonstration of an expanded CAG repeat in the gene for DRPLA was used to confirm the diagnosis.

A Case of Systemic Lupus Erythematosus Presenting with Amaurosis Fugax without Antiphospholipid Antibodies Syndrome.: Jung Hyun Kim, Jung Sang Hah, Mee Young Park, Se Jin Lee, Jun Lee; Yeungnam Univ J Med. 2006;23(1):113-117. Published online June 30, 2006; DOI: https://doi.org/10.12701/yujm.2006.23.1.113

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Abstract PDF: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that may affect many organ systems including the nervous system. The immune response in patients with SLE can cause inflammation and other damage that can cause significant injury to the arteries and tissues. A 48-year-old woman was admitted to the hospital because of transient monocular blindness. Magnetic resonance imaging and conventional angiography showed severe stenosis of the distal intracranial internal carotid artery. The patient was diagnosed as having SLE but the antiphospholipid antibodies were negative. Amaurosis fugax has not been previously reported as an initial manifestation of SLE in Korea. We report a patient with a retinal transient ischemic attack as the first manifestation of SLE.

Neuro-Behcet's Disease Presented with Cerebral Venous Sinus Thrombosis: A Case Report.: Yun Kyung Lee, Mee Young Park, Seung Hyun Lee, Sung Gyun Joo, Yong Kook Cho; Yeungnam Univ J Med. 2004;21(1):96-100. Published online June 30, 2004; DOI: https://doi.org/10.12701/yujm.2004.21.1.96

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Abstract PDF: Behcet's disease is a chronic, relapsing multisystem disorder, that may develop into variable neurological manifestations. They include vascular and parenchymal involvement. Vascular involvement is dominated by cerebral venous sinus thrombosis marked by benign intracranial hypertension. Cerebral venous sinus thrombosis can present with all the classical criteria for idiopathic intracranial hypertension, including normal brain CT findings with normal CSF content. But brain MRI is a useful diagnostic method in this situation to confirm the presence of cerebral venous sinus thrombosis. We experienced a case of raised intracranial pressure in a 21-year-old man, caused by cerebral venous sinus thrombosis. We disclosed his symptoms and signs thus fulfilling the diagnostic criteria for Behcet's disease.

Generalized Chorea-Ballismus Associated with Nonketotic Hyperglycemia in Diabetes Mellitus: A Case Report.: Hyun Ran Shin, Ji Hoon Kim, Mee Young Park; Yeungnam Univ J Med. 2002;19(2):136-143. Published online December 31, 2002; DOI: https://doi.org/10.12701/yujm.2002.19.2.136

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Abstract PDF

Even though the nonketotic hyperglycemia is a metabolic disorder, it complicates hemic- horea-hemiballism rarely. Moreover, generalized chorea-ballism associated with nonketotic hyperglycemia in diabetes mellitus is very rare, so it has not been reported in Korean literature. Although the precise pathophysiologic mechanisms of these disorders are still poorly understood, deficiency of gamma aminobutyric acid (GABA) in nonketotic hyperglycemia or reduced GABAnergic inhibition by striatal lesion may increase inhibitory output to subthalamic nucleus. These result loss of pallidal inhibition and produce contralateral hemichorea-hemiballism. The striatal lesions, such as transient ischemia with reactive astrocytosis or small amount of petechial hemorrhage, are related with changes of magnetic resonance image (MRI) findings presumably. We report a diabetic old woman who developed generalized chorea-ballismus as a very rare complication of nonketotic hyperglycemia. Her brain MRI showed high signal intensity in left lentiform nucleus and right pallidum on T1 weighted images and low signal intensity in bilateral putamen on T2 weighted images with highly enhanced corresponding lesions on T1 weighted enhancement images.

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A Case of Type 2 Diabetes Mellitus Initially Presented as Monochorea Associated with Ketotic Hyperglycemia
Si Hyeong Lee, Dong Woo Lee, Yeong Min Lee, Tae Kyun Kim, Min Jeong Kwon, Soon Hee Lee, Jeong Hyun Park
The Journal of Korean Diabetes.2014; 15(4): 244. CrossRef

Lateral Femoral Cutaneous Nerve SomatosensoryEvoked Potential Study in Normal Adults.: Seung Sik Moon, Mee Young Park; Yeungnam Univ J Med. 2001;18(1):67-74. Published online June 30, 2001; DOI: https://doi.org/10.12701/yujm.2001.18.1.67

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Abstract PDF: BACKGROUND
Meralgia paresthetica(MP) which is characterized by paresthesias and sensory impairment without motor weakness in the anterolateral aspects of the thighis produced by compression of the lateral femoral cutaneous nerve(LFCN). Even though the diagnosis of MP is mostly based on the clinical symptoms, electrophysiologic study is mandatory to confirm the disease objectively. It has been known that Somatosensory evoked potential(SSEP) study of LFCN is a simple and very useful method to evaluate MP, so we studied SSEP of LFCN in normal adults and offer normal values. MATERIALS AND METHODS: Thirty six normal adults(23 males and 13 females) ages from 21 to 73 years old(mean+/-SD:42.06+/-15.74) were studied SSEP of LFCN bilaterally. The stimulation site was anterolateral aspect of thighs and the recording site was Cz'. RESULTS: The mean values(msec+/-SD) of LPo, SPdegree, LN, and SN1 of all subjects were 35.10(+/-2.42), 33.80(+/-2.4), 43.68(+/-1.88) and 42.16(+/-2.12) and the mean values(msec+/- SD) of DPo, DNl and DA(tw+/-SD) were 1.3O(fi1.14), 1.52(+/-1.38) and 0.32(+/-0.33). CONCLUSION: For the diagnosis of MP, comparison of latency difference between both sides is more reliable than simple value of latency itself because of individual differences of body types. According to our results, the latency difference should be less than 2 msec and the amplitude difference was less than 1.6 times in normal adults.

Driving of Motor Vehicles of the Epileptic Patients.: Yeung Ju Byun, Mee Young Park, Jung Sang Ha; Yeungnam Univ J Med. 1994;11(1):16-29. Published online June 30, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.1.16

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Abstract PDF: No abstract available.

The risk factors of recurrent ischemic stroke: Cheol Jung, Wook Nyneon Kim, Min Jeung Kim, Soek Mum Choi, Kyung Yoon Eur, Mee Young Park, Jeng Sang Hah, Yeung Ju Byun; Yeungnam Univ J Med. 1993;10(2):423-431. Published online December 31, 1993; DOI: https://doi.org/10.12701/yujm.1993.10.2.423

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Abstract PDF

To evaluate the risk factors which are related to recurrence of ischemic stroke, we selected subjects who were admitted to YNUH due to recurrent stroke and compared their risk factors with non-recurred group- who suffered from single ischemic stroke. In the subjects, 55 of them are men and 22 were women and in the non-recurred groups, 84 of them were men and 40 were women, Subject's age ranged from 29 to 86 years (Mean 62.5years), and non-recurred group's age ranged from 27 to 90 years (Mean 60.7years), Peak incidence of ischemic stroke is in the 7th decade in both groups. Age and sex are not statistically significant for recurrence of ischemic stroke. The patient's history of diabetes mellitus, myocardial infarction, atrial fibrillation, transient attack and type or site of ischemic stroke had no significant effect statistically on the recurrent ischemic stroke. However, when the patient had previous history of hypertension or systolic blood pressure more than 160 mmHg and diastolic more than 95mmHg, there was substantial difference (P<0.05) between the two group in the recurrence of ischemic stroke. According to the above results, hypertension is most likely significant risk factor of the recurrence of ischemic stroke within 2 yers after initial one. Therefore, adequate treatment of the hypertension is important for the prevention of ischemic stroke. Further study is required for searching other risk factors.

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Hemiplegic Experience after Stroke among Middle Aged Man
Soo-Yong Oh, Jeong-Seop Lee
Journal of the Korea Academia-Industrial cooperation Society.2016; 17(5): 582. CrossRef
Knowledge, health‐promoting behaviors, and biological risks of recurrent stroke among stroke patients in Korea
Hei Ryun Lee, Ok Kyung Ham, Young Whee Lee, Insook Cho, Hyun Soo Oh, Joung‐Ho Rha
Japan Journal of Nursing Science.2014; 11(2): 112. CrossRef

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